Research by Les Simpson, PhD
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Leslie Owen Simpson, born 4/14/24, widower
BSc, 1951, University of New Zealand, Biology;
MSc, 1953, University of Otago, Zoology
PhD, 1971, University of Otago, Experimental Pathology
1954: research assistant, Dept of Surgery, U of Otago, organ and tissue transplantation
1955-61: WHO lecturer - established the biology deptment at Central Medical School in Fiji for students from all over the Pacific
1962-64: Sheep farming
1964-85: senior research officer, Dept of Pathology, U of Otago
Dr. Simpson's research interests are embodied in approximately 86 papers, chapters in three books, and dozens of letters to scientific journals. He has lectured widely in America, Asia, Europe, the Pacific, and South Africa. Since retirement in 1985 work continued as honorary research officer in the Department of Pathology and the Department of General Practice.
From the early 80's the study of blood rheology became a major interest that burgeoned when it was shown that red blood cells could be classified into six different categories according to shape. Dr. Simpson has shown that when the environment of the red cell is changed, the shape also changes. Many different triggers initiate this change in shape, ranging from viral infections to emotional upsets. For reasons which are not understood, in those with chronic disorders changed red cell shape populations persist for a long time. This affects capillary blood flow adversely so that the rate of oxygen delivery becomes inadequate to sustain normal tissue function. This dysfunction may be manifested by symptoms in any region of the body. Such changes will be most significant in tissues having a high rate of oxygen utilization, such as muscles and nervous tissue. This general philosophy was embodied in a 1997 paper titled: "Myalgic Encephalomyelitis: a haemorheologic disorder manifested as impaired capillary blood flow."
Dr. Simpson's Seminar and Treatment Protocol
In October (2000) Les Simpson, PhD. spoke on abnormal red blood cell morphology (shape) in CFIDS, FMS and MS and other chronic conditions. He discussed the six shapes of RBCs (red blood cells) and presented slides showing a direct correlation between changed shape populations and severity of illness. Healthy RBCs are flexible enough to squeeze through the capillary system, carrying oxygen and nutrients to tissues and organs. Comparatively, the RBCs of chronically ill patients are more rigid and change shape. The increased rigidity and altered shapes of the RBCs compromise capillary blood flow and impair the delivery of oxygen and nutients to tissues and organs of patients. Dr. Simpson has also found that chronically ill subjects often have smaller capillaries, further compounding the problem of blood flow.
Dr. Simpson had found treatment recommendations to reduce the rigidity and altered shapes of RBCs, thus improving circulation and reducing symptoms.
1) Reduce stress - it alters RBC shapes, impairing flow.
2) Engage in physical activity, however modest, to improve circulation but avoid any acitivity that leads to relapse.
3) Take Evening Primrose Oil. A double blind study revealed EPO improved capillary blood flow in a significant number of patients. Dr. Simpson recommends the brand Efamol, though any product that contains less than 10% GLA should be effective. Seacoast Natural Foods, 800-555-6792 carries an Efamol EPO product called "Restore" for less than half the normal retail price. Take two 500 mg. capsules with each meal and two at bedtime. If EPO is going to help, improvement will be seen within six weeks. One group member reported after several days of taking Efamol EPO she had warm hands for the first time in years. An alternative to EPO is salmon oil and/or gingko biloba. He recommends the brand Ginkoba. There is also a prescription drug called Trental which has a similar effect.
4) Dr. Simpson has found that injections of hydroxycobalmin (British B-12) positively affect on RBC shape, thereby improving blood flow.
A video tape of Dr. Simpson's seminar is available for $19 (including $5 contribution toward his current research). To order, contact Carol Sieverling.
This information came from our January 2000 newsletter.
Drink More Oxygen!
That's the slogan of Rain Fresh Water, who provided the free bottled water at the Les Simpson Seminar. Their water goes through a 24 step process, including triple carbon filtration. KDF media, micro filtration, ozonation, an ion exchange, reverse osmosis, magnetic treatment, ultra violet lattices, and enrichment with medical grade O2.
This process is designed to reproduce rain water from an unpolluted environment, the healthiest type of water. Many thanks to Obbie and Lori Loving of Rain Fresh for their generosity. You can contact them at 817.577.3800.
This information came from our January 2000 newsletter.
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