Various info from CFSFMExperimental (yahoogroups) and similar lists:
Message: 13
Date: Mon, 16 May 2005 10:31:25 -0700
From: Martin Pall <martin_pall@wsu.edu>
Subject: Re: Q10 question/ prof. Pall
>
>Marty, seems I remember reading you saying that Q-10 can be good for us however it could turn out to be bad but I forgot why. I am in Mexico for the summer and been out of touch for awhile. I have been on °-10 for several years, as well as Vit. C, E and A, and I started out with around 30mgs/day and now I am up to 120mgs twice a day. Is this too much?
My impression is that the optimal dosage of Co Q10 varies
considerably from one individual to another. That may be because the
absorption of fat soluble compounds in general shows considerable
variability among individuals. In general, these should be taken as
gel caps (dissolved in vegetable oil within the gel cap) in order to obtain better absorption. I personally took (and still take) 75 mg, once per day in the morning and this may be a reasonable dose to
start with but, I think that there is all of this individual variation, so optimal dosage may vary (my guess is from 30 to perhaps 200 mg).
Please remember that I am a Ph.D., not an M.D. and none of this should be viewed as medical advice.
--
Martin L. (Marty) Pall
Professor of Biochemistry and Basic Medical Sciences;
Washington State University
phone 509-335-1246;
fax 509-335-9688
From: "kattemayo" <kattemayo@...>
Date: Mon May 16, 2005 4:25 am
Subject: Impedance,Echo, Diastolic Heart Failure
Dr. Cheney gave me a history of this field...other figures later.
Diastolic Heart Failure has only been seriously studied in the last 10 years. (Known or suspected for 30?)
The Impedance machine, used in
Peckerman study and Cheney's ofc is only 4 years old. Therefore, only Dr.s in
Medical School in the last 4 years are trained in it.
A breakthrough of this is that it measures heart function while tilted and
sitting (to evoke standing such as at 30 and 70 degrees...and sitting with feet
down... postural conditions...in addition to supine (lying down).
The Echocardiogram that he does is on the Echo "Vivid 7" machine, made by G.E.
Licorice: This information is a collection from several posts (05 Apr 2005).
This person speaks of using low-dose licorice to help support the adrenals for several years now, although not every day though. Instead, they alternate it with other treatments (salt or cortisol) that also support adrenals. They say that many people (with adrenal problems) use licorice with no significant side-effects, although obviously there are bound to be some who get some side-effects.
They state that licorice is a type of re-uptake inhibitor for cortisol and a stimulant to the adrenal cortex in general. So people with low cortisol often benefit. [I assume they mean the type with the
glycyrrhizin.]
Supposedly, the rapid fluid intake (weight gain) means you may have been dehydrated. Licorice helps the adrenals regulate salt levels and manage hydration. Taking some salt in water a few times a day will have a similar effect, but without the licorice. [They were speaking to a person who had been given licorice via IV and had, consequently, gained three to five pounds in 24 hours.]
Licorice root is known to stimulate the adrenal glands and to block the breakdown of active cortisol in the body. It takes 2.5 grams of licorice root daily to makea significant improvement in CFS. While there have been no large clinical trials to test licorice in patients with CFS, it may be worth a trial of six to eight weeks using 2-3 grams of licorice root daily.
Fast Heartbeats: There was a report from one of Dr. Cheney's patients who had recently seen him (02 Mar 2005):
"... he has now found a number of his patients
that are exhibiting diastolic heart failure, including myself. He
received a grant from one of his patients for a special heart machine and
has used it on 8 of his patients. So far my tests showed that my heart
function was one of the worst that he has seen, yet for the most part I
am able to work almost full time.
"A few years ago, when I took a treadmill test it showed that not enough
blood was getting to my heart. When the Docs did an angiogram they found
that my arteries were clear and really didn't offer much of an
explanation. Well, Dr. Cheney has found the problem. Apparently,
because we are energy-deficient throughout our
body, including our heart, our hearts don't produce enought energy to
stay open long enough to receive a proper amount of blood, hence the
explanation for the treadmill test not showing a proper amount of blood
in the heart. To compensate for this defect, in part, my
heart rate is generally above 100 beats a minutes. However, even with
that, my oxygenation level is only around 94.
"GE is so interested in the tests that they are bringing one of their more
expensive echocardiograms with their best technicians. Approximately 10
years ago, this problem was discovered by a researcher at the University
of San Diego.
...However, for those of us who
have fast heart beats, this may be the problem."
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